clicking problem

Hey guys, My computer is infected with the double click cookie (virus). I have tried every software to try and remove it and I have followed instructions to go into my registry and try to fix it, but it is still double clicking when I click once. I hope someone here has a solution to this...

32 bit W7, fresh, clean install and I have an intermittent issue where the mouse turns to a very pretty spinning blue circle and I can't click on anything. Any help would be greatly appreciated. No app's running at the time. TIA.