What comes to mind for me is a possible problem with some add-ons or accelerators. I suppose it could also be acceptance of cookies or popups. Can you try to disable selected ones to see if the problem stops.
I was on a page yesterday that wanted to install a cookie and the default settings would not allow it to do so. I altered those settings for testing and the process was completed.
Are you running the x64 version of IE?
Have you tried the version with no add-ons you should be able to access from the Start Menu?