Basically, this issue seems to pop up at any time, with no warning, the only common thread being that some sort of audio is on. Sometimes it goes for hours without it, even a day, other times it crashes with barely five minutes' break between crashes. If the audio distort is in a program, for instance a game, sometimes I can avoid the lockup by instantly quitting it. GTX 275 video card(latest nVidia drivers installed) Intel Core i7 920 processor ASUS P6T motherboard Windows 7 Professional 12 GB RAM, DDR3 Not sure what'd really be relevant besides. I have made no major new installs recently, except in an attempt to rectify the issue(Installing CPU-Z for more PC data, installing RealTek audio drivers). The issue first popped up while playing Mass Effect 2, and seemed to disappear for several days after uninstalling and reinstalling ME2, and only happened during that game for a while. Then it happened while playing Call of Pripyat, and now while doing nothing in particular other than listening to music(though it seems to often coincide with opening Internet Explorer... normally I use Opera.).