I'm using: OS - Windows 7 Ultimate 32 bit CPU - AMD Athalon XP 2400+ 1.99GHz RAM - Kingston 2.00 Gb MOBO - VIA VT 8366a Apollo KT266a the problem I have is an 1Tb Western Digital external USB drive. It will work fine, but every now and then I can't access anything on it. I can browse the folders, but they all say they're empty. I try to disconnect it with the Safe USB Device Disconnect thing, but it says "this device is in use". I try to unplug USB cable, replug - no luck. same with power cable. The only thing that gets it back in gear is rebooting windows. A side note that may or may not be related, Windows 7 will often have processes that don't respond and CAN'T be killed in Task Manager (you MUST hard reboot). I ran ComboFix and TuneUp Utilities 2009 Registry Cleaner - which seems to make that happen less often, but it still happens and usually has to do with a program that's accessing a file off my external drive (all my music, movies, pictures are on that). I've read plenty of posts around the net about windows 7 and usb hard drives having similar problems, but no solutions.