Framework Error

Alright so when I used to startup this framework error appeared:
Invalid root in registry key

Someone here mentioned to just go in and delete the win64dll so I did and don't get the error BUT I cannot run a specific autodesk program and autodesk said that it is a javascript error of some sort, and I am guessing it has to do with this error somehow.
The error mentioned above also comes back after a while after deleting.

Is there a program or method to fix all of this?
I have tried free programs but none have worked.
Or should I just do a clean install and be done with it?


EDIT: here is the link to the autodesk error I am getting:

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