User accounts

C:\ Users lists SIX user accounts, some of them with massive data.
Control Panel / User Account lists only THREE User names: Administrator, Standard User and Guest.
Users Properties / Security / Group or User Names lists four: Everyone, SYSTEM, Administrator (one only) and Users (one only).
Do I need to get rid of the accessed accounts in C:\ Users?
if yes how?
May I have your thoughts please.

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