Most agree it's a BAD idea to run more than a single AV/AM app in real time as they can conflict with each other. Stop one or the other. I personally use MSE on all our PC's with excellent results. If you read what MS states, they recommend shutting down all apps before installing updates. This includes your AV apps. What I do is download updates, disconnect from the internet, shutdown apps, then install the updates. Works every time.