Yes, there are several software options available that allow you to take high-resolution screenshots in Windows 10.
1. Snagit - Snagit is a popular screen capture and screen recording software that offers advanced editing features. It allows you to capture screenshots in high resolution up to 3840 x 2160 pixels. You can also set custom DPI settings for your screenshots.
2. Lightshot - Lightshot is a lightweight and easy-to-use screenshot tool that lets you capture screenshots of specific areas of your screen. It allows you to save screenshots in various formats, including high-resolution PNG and BMP formats.
3. Greenshot - Greenshot is a free and open-source screenshot tool that offers advanced features for capturing screenshots. It allows you to capture full-screen, specific windows or regions, and offers custom DPI settings for your screenshots.
4. PicPick - PicPick is a versatile screenshot tool that lets you capture screenshots, edit them, and save them in various formats. It offers advanced screen capture features, including the ability to take screenshots in high resolution.
All of these tools provide an easy and efficient way to take high-resolution screenshots in Windows 10 without changing your monitor's scale settings.