I wouldn't risk it Cheemag as there are simply hundreds if not thousands of security fixes in those updates. Some will close vulnerabilities found within the os which neither kaspersky or Malwarebytes will cater for so yes you do need them really.
If you have your update settings on 'check for updates but ask me whether to download and install them' you can simply check off a few updates at a time. I used to do this and it takes the strain off somewhat.
Try installing them in batches of 10 or 20?