Cursor inaccuracy could be related to mouse as well as the application. Please check in other paint application to confirm the same. Alternatively, you can check with another mouse to validate. By now, you should be able to know where to focus.
If mouse is the culprit, it could either be the case that the mouse is faulty or the driver is bad.
If working with another mouse doesn’t reproduce the problem, this indicates the status of the mouse. If the problem persists with other mouse, then check for new driver from the manufacturer’s website. Downloading the same should fix the alignment problem.
To verify if Mspaint is the culprit, verify by creating a test user account.
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