Hello and welcome to the forum.
I have this sneaky hunch that we may be seeing more and more of this as Windows 8 matures and becomes more widely used. Especially as it pertains to older peripherals like printers, scanners and AIOs.
The fault is not with Microsoft or with Windows 8, but with the OEM in this case Epson, not updating their drivers. As in this case Epson has marked this as a "Discontinued Product" http://www.epson.com/cgi-bin/Store/consumer/consDetail.jsp?oid=28907797 so I would suspect that your options going forward with this device on a new OS might be limited.
Did the device work formerly in Vista or Windows 7 (32 and or 64bit version)?
If so you may find some success if you try setting the properties of the installer (usually Setup.exe) to use Windows 7 or Windows Vista compatibility mode, I would also check the box that says "Run as Administrator" and see if that helps. (Right click it, choose properties, select the Compatibility Tab and check the appropriate boxes).
Regards
Randy