When you install a program and it asks where to put the programs you want on the slower drive, just change the path to just that. For instance "D:\Program Files\Program Blah" Do be aware that most programs will still save some data on your C drive however, you really won't get away from them taking some space up from shared DLL files for instance, or some program data. But usually directing it to use your other drive for the install gets the majority of the data over there off your SSD.
I'd suggest putting the programs you use the most on the SSD, and the ones you use the least on the spinner.
If your a gamer Steam allows you to make multiple Steam Library folders, which is very useful, you can put games that you play the most on C and the rest on your spinner drives.