It would be 'possible' but you'll need to reinstall all the drivers, especially for the motherboard and on-board features, since it looks like the chipsets of the 2 boards are different. To prevent issues from cropping up down the line, I strongly suggest that you back up all your data and do a clean install on a freshly formatted HDD since this seems to be a major upgrade.
Recently, I swapped out my Asus P8P67 mobo under the Intel Sandy Bridge recall scheme, but since the replacement mobo was exactly the same model (just a revision change), I was able to escape with no changes other than a reactivation of Windows, Office and a couple of games. Your case is slightly different.