That is a strange one, and unless you have been changing the security settings, possibly a virus is at work.
I will assume you have not been able to get into Safe Mode and remove the drivers or disable the device?
If that is the case, I would probably try to rename the file from the Command Prompt and use a .bak or .old extension, if it will allow. You could try deleting it, but then a recovery might be harder. I suppose if it found one file bad, there may be others but I do not know.
If you feel like experimenting, you might open the Command Prompt, probably in some Administrative fashion, and type ICACLS to see what options you might have. I have not personally tried this, so completely up to you and I suppose there is a chance...