Not Neccesarily.
It may depend on the manufacturer. I have changed one or two Dell motherboards lately. It is there preference, rather than investigate individual motherboard item problems.
On every occasion, when logging in with the users MS account, They have been automatically activated again, with no input. In the motherboard delivery package in the even of extreme problems, there is even a new key in order that the user may start over.,
Nigels solution should work, but, important, at the beginning of the installation, do NOT put in a key, it is not required and will fault your installation.