Cumulative update KB4482887 can affect gaming performance.


Windows Forum Admin
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Microsoft have revealed that the last cumulative update for Windows 10 build 1809 KB4482887 can affect gaming:

After installing KB4482887, users may notice graphics and mouse performance degradation with desktop gaming when playing certain games (eg: Destiny 2).

Microsoft is working on a resolution and will provide an update in an upcoming release.
As a short-term resolution, users can uninstall KB4482887 to regain performance.

Read 'known issues with this update'