I would think that the best bet would be to put all the apps that you want to install on the client machines into one folder and share it. That would let you run the installer across the network, however; as far as updates to the latest signatures, some apps will let you download the signatures separately and so you could add those to the shared network resource (folder) as well, while other require you to update the signatures from within the application itself. Don't know of any that let you slipstream the latest signatures into the installer.
Best of luck, if you come up with another solution let us know.
Randy.