I have not seen that message. Do you know what software package it is referring to?
Have you checked into any of the current malware that seems to lock your system? Have you gotten any messages about paying to unlock the system?
You might try opening msconfig.exe and setting it to load just the Microsoft drivers. Maybe that would allow you to get into the normal system. You should be able to run it using the mouse since it is in the Windows\System32 folder.