Although I wouldn't recommend running Windows defender as your sole protection. Malware isn't always the reason for a slow computer.
- A dirty fan or heat sink can cause the CPU to throttle
- Too many processes running a system
- Cheaper hardware obviously will make for a slower computer
- Failing hard drive
I'd start by providing your system specs and the running process information.
The latter can be dumped from powershell with the following command
Get-Process | Export-Clixml -Path $env:USERPROFILE\Desktop\process.xml