I recently upgraded to Windows 10 from Windows 7 Home Premium. I am experiencing an issue that appears similar to an post several months ago that I see no resolution to. Wondering if anyone else is having an issue like this. The previous user's issue after a new Windows 10 build from March or April read like this..... ".....My keyboard works, my mouse pointer moves but I cannot click any where. When I move/click on mouse, I got a crazy sound. Also the Win Key works, and my start menu is opened. I can move around my apps through the keyboard. But my mouse is crazy. PLEASE HELP ME....." I cannot write it any better. I believe I have isolated it to when I unplug a USB game controller. Immediately after that my mouse pointer will move freely, but mouse clicks do not work. After a number of attempted mouse clicks it appears a buffer fills up to maximum because the computer beeps with each additional click and when that begins the mouse pointer becomes erratic. This is a desktop computer, does not have a touch pad or touch screen, so lets get that out of the way. The USB wireless keyboard and mouse are both Microsoft 4000 and checking the driver in Device Manager returns that the latest driver is already installed. The USB gaming devices are a Saitek Pro Flight Yoke and a Saitek Multi Panel USB switch console. Both devices are plugged directly in to USB ports on my CPU. They are plugged separately. I tested with both of them plugged in at the same time (they are most commonly used together), and plugged in individually. It appears to make no difference. As soon as one or the other is unplugged the mouse issue begins. I can access the Start menu via the keyboard and choose Shut Down or Restart, but once the screen indicates the action is taking place the state of the computer stalls. It never finishes the power down. The only resolution is to physically boot down the computer by holding the CPU power button down. Anyone seen this problem mentioned before? And any successful resolution?