Hi,
did you try the built-in Windows System Restore to roll your system back to a point in time before the profile problem occurred?
If this doesn't fix it, I would
MAKE CERTAIN YOU HAVE ALL YOUR PERSONAL DATA (LIBRARY FOLDERS) BACKED UP TO EXTERNAL MEDIA BEFORE ATTEMPTING FURTHER REPAIRS WE RECOMMEND TO YOU!!!
From here, you'll need to test your hardware using the link to the article I wrote. Once you've done this, you can proceed to software troubleshooting and repairs also covered in the same article. There is no sense running software repairs on a computer that has broken hardware, as the problem will just appear again. Here's the article:
Windows 10 - Unclickable Task Bar
Start with
POST #6 under my...