Desktop does not respond to mouse actions as previously nor the front panel power switch. I have to disconnect the power cord, reconnect, and press the front panel power button. Then the unit starts up and returns to window without the login window as if it was sleeping. The problem started after my attempts to install a defective external drive enclosure connected with an esata cable. I have since obtained a working external enclosure connected with an esata cable. The present Sleep wakeup malfunction is now present with or without a working external drive.