Doesn't seem to work unfortunately, I created the TcpAckFrequency Dword value and set it to 1 and it didn't do anything. Another thing worth noting is that HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSMQ\Parameters doesnt seem to exist in vista or windows 7, so setting the TcpNoDelay value doesn't work. After googling a bit more it seems that Vista needed a hotfix in order to disable nagle's algorithm, perhaps Windows 7 is the same.