I don't use skype, however since I use my webcam in other applications, when I installed windows 7 64bit, I let windows 7 install the drivers. I have been able to use my Logitech Orbit Sphere in MSN messenger, Yahoo Messenger, to take photos on facebook....etc without any issues. However, at the moment, I do not have the software installed. I am going to try the driver for windows vista (qc1051enu_x64) on the Logitech website first before I dig out the cd I have the older software installed on and see if that works with Win7 64bit.
When I had windows 7 32bit installed, I had a problem getting the camera to work with the software. I actually stumbled upon a forum that had a fix for the problem. Install an older driver software. I did, and it worked just fine. I didn't even have to run it in compatibility mode. I could move the camera around and the software was fully functional with no issues.
I just dug out my cd and found the driver software. I am not sure what operating system I downloaded it for, but I used it on Win7 32 bit with no problems, so I suggest doing a search for it if you want to give it a go (if I don't re-post with my findings yet).
qc1110 that is, quickcam version 11.1.0
~LadyAshura