I couldn't get mine to work either. I then tried to install in the driver in XP SP3 compatibility and run as administrator and that was the first time the driver installed. I installed the Canonscan Toolbox the same way and now the scanner works perfectly. Hope this helps someone. Forgot to add the scanner worked fine in Vista 32. I tried to initially install in Vista compatibility then both Vista SP1 and SP2 and it didn't work. This was on build 7100 and now 7260.