This worked for me - found it on another Q&A
Re: (Unofficial) drivers for Epson Perfection 1660 scanner
What did work was installiong the x64 driver from Epson for their Epson Expression 1680 Professional scanner instead. I had to force the Device Manager driver install to use the .inf file for the 1680.
Here's how:
Download and run the Epson file.
It will extract to here:
C:\EPSON\epson12203_twain_driver_and_epson_scan_utility_304a
(
I didn't have to do this )Then cancel the install process.
Did following:
Open Device Manager.
Right click the scanner (will have yellow "!")
MINE DIDN"T click update driver, click click :Browse my comp", click "let me pick from list..." , click have disk, then browse to here:
C:\EPSON\epson12203_twain_driver_and_epson_scan_utility_304a (pick any inf, and it should go from there.)
Did the .inf but not sure if it worked- I clicked on the set-up.exe file.
The scanner worked!! Had an Epson scan icon on desktop & that opened right up.( Like interface better, too) Also scanned into Word as a .doc ( smaller file) after I had it use the 1680 in my scanner of choice. I had been trying for about 2 months to solve this so I didn't have to buy a new scanner. What a relief. Now I just have to try it in Photo Elements. Hopeit works for you.