The original poster, johnson, inquires if they can use the Windows 10 ISO on another Windows computer after removing it from a Mac, expressing concern about hidden activation codes. Neemobeer confirms this is possible as long as the software is properly removed from the Mac. Johnson responds, questioning whether Windows 10 activation is tied to specific hardware, indicating some uncertainty. The overall sentiment suggests a cautious but optimistic view on transferring Windows 10 installation between devices.