It's 2010, and I'm still getting the same blank error screen when trying to open a PDF document in a browser window with Windows 7 and any browser (IE8, Firefox, etc.). Here is what the box looks like: To help describe my situation, I am creating PDF documents on the fly through PHP. I've been doing this for years without a problem until today, when I freshly installed Windows 7 on this computer. Now, the above blank error message pops up completely at random. Sometimes, the PDF opens fine; sometimes it shows the blank error box and doesn't show anything. I have tried opening the same PDF document every time as a constant, and it does work sometimes, so I know the PDF does work some of the time. I tried reinstalling Adobe Reader 9.3 - no luck. I tried uninstalling Adobe.com and Adobe AIR - no luck. I tried clearing the browser cache - no luck. I tried changing some of the headers through PHP - no luck. Are we just SOL with this problem? I can't believe Adobe or MS hasn't fixed this yet. This is incredibly annoying.