Mr Shifty does look extremely buggy especially if its the Nintendo version.
The only real obvious thing is to update your system drivers. Some of the updates are only a few months later than the originals but better than nothing: GA-Z77X-UD5H (rev. 1.1) | Motherboard | GIGABYTE
Downloaded and installed them all. Will test Mr Shifty again. I almost wish the game would Bluescreen like it did before, so testing it would take a minute and not an hour.
If that Mr Shifty game crashes or blue screens again then try another driver. I know Nvidia released a new driver today which you can find in our software update section. Oh and don't forget to use the DDU.
Tested it out. Didn't get a Bluescreen this time, just went black and turned off. Bluescreenview didn't have a log. Updating graphics driver again (with DDU of course), but I'm starting to worry that this just won't go away.