The CSM (Compatibility Support module) is part of the UEFI enabled boot. It is used to set the system to full secure boot, or allow for other types of UEFI installs. The other bios mode is Legacy or MBR, which is the old form of Bios and is not capable of Secure Boot.
If you have a Windows 8 system capable of secure boot, which would include any add on video cards, you should be able to turn on Secure Boot and Disable the CSM and be able to boot. Windows 8 should still boot if CSM is enabled, since it is not required for Windows 8 to have to be set to Secure Boot. If you want to boot Windows 7 in UEFI mode, you would have to enable the CSM.
Having said that, it should be noted there are many ways OEMs are implementing the Secure...