I had a lot of issues with my Sound Blaster card in Windows 10.
Nothing I found would fix it, so I switched to my on board sound.
I don't really hear any difference in the sound, it sound basically the same, and my problems all went away.
A picture of your sound control panel might be helpful in figuring out what your options are.
Here you can see my options for both the Sound Blaster card and the Realtek On Board options.
While it always shows that the Sound Blaster is "Ready" it doesn't work when I plug in the speakers and try it.