Windows 10 How to omit a drive from backup

[BigRedArtSet]

As the image explains, I do not want to back up the S: drive, but I still want to backup the rest of the locations in that checkbox (Reserved, C:, Recovery)

How can I remove the S: drive from that check box?

 

[livix07]

You can temporarily disconnect the S: drive (assuming it is a different physical disk).
There are other free software for back up that might give you the possibility to omit that drive.