Hello and welcome to the forum.
Perform a chkdsk on the Drive where the files are being stored.
chkdsk C: /R
answer "Y" = yes when prompted
reboot the computer and wait for all five stages to complete
check the results in event viewer.
You may also want to perform a memory diagnostic
Download Memtest86+
from this location here. Burn the ISO to a CD and boot the computer from the CD from a cold boot after leaving it off for an hour or more.
Ideally let it run for at least 7 passes / 6-8 hours. If errors appear before that you can stop that particular test. Any time Memtest86+ reports errors, it can be either bad RAM or a bad Mobo slot. Perform the test RAM sticks individually as well as all possible combinations. When you find a good one then test it in all slots. Post back with the results.
See
this Guide to using Memtest 86+
Those are the two most likely culprits for file corruption, although I would expect more broader problems, even with your OS files if it is hosted on the same drive as the files where you are experiencing the corruption.
Regards
Randy