Hi,
sounds like you may have some corruption within the os itself. Try running these scans:
File scans
Right click on the Start menu icon and from the revealed list choose 'admin command prompt'. Type:
sfc /scannow
press enter and await results
In the same command prompt and after the above scan has finished type:
dism /online /cleanup-image /restorehealth
Press enter and await results (longer this time).
If the first scan found files it could not repair but the second scan is successful, run the first scan again using the same command prompt box and this time it should repair the files found.
As for issues with updates, try running the update troubleshooter from Microsoft:
https://support.microsoft.com/en-gb/help/4027322windows-windows-update-troubleshooter
Can you post the make and model of your mouse please.