Haven't bothered with Defender as it always scores low for the last 2 or so years. The uefi is set to the defaults, except my ram which has to be clocked down to DDR3 2133 per G-Skill. It's DDR3 2400 ram. Only turns off if I run the full scan's. That may not be the case, though. It's pretty much on 24/7, but I restart it between 7-10 times daily.