I've got exact same problem with Crysis and UT3 ! It's freaking me out! Tryed compatibility mode... It doesn't work.
Config:
Windows7 RC 7100 x64, nvidia driver 190.38, Comodo internet security antivirus.
I think that antivirus is messing all up - I have played UT3 succefully while I had avast! antivir installed. The problem is that I hate avast! and it's not really 64-bit app.
I cant beleive this post has gotten this far without somebody mentioning the cd problem with crysis!!!!
The only way I can get crysis to run is to insert the origenal game cd, then goto my computer/dvd drive then locate the autorun exe and double click it.
when the splash screen appears click play!! don't try running it from the my games folder. it don't work!!
I have two pc's running win7 64bit and they both run crysis with "4xaa @1920/1200" and "2xAA @ 1650/1050"respectivly
system 1 = Q9650, striker2extream, 280gtx, 4gig ddr3 corshair dominator. System2 = Q6600, xfx680i lt, 9800gtx, 2gig corshair sli 800hrtz ddr2