I agree with MalwareBytes. I prefer Auslogics Disk Defrag to Defraggler since Samsung uses it internally and they are a fantastic company. I would not touch the registry with CCleaner with a 10-foot pole in a work environment. In my opinion, if you are going to start chopping up the registry using automated software, you need not consider the one being paid for by toolbars on the install screen. I would only go with commercial software for automated system maintenance and this list does include RegistryBooster, TuneUp Utilities, and Ace Utilities. Many of these utilities are capable of moving the registry up to the front of the partition table for better performance and are good for aging systems. I cannot honestly trust any non-commercial registry cleaner due to the absolute carnage it could do to a system. At least with commercial applications you have a monetary investment in research and development and these companies work hard to achieve Microsoft Gold Certified status. I didn't start thinking this way until I saw a few systems literally annihilated by CCleaner. Granted they were old and unattended for who knows how long, but we are talking about install dates of 2001. Nonetheless, this never would have happened with better software to carefully manage the condition of the system. When I say I endorse certain products commercially, I really do, for the betterment of forum users, and this does include, especially anti-virus and registry cleaners. Otherwise, I absolutely agree with SuperAntiSpyware, HijackThis!, and MalwareBytes.