Windows 7 I can't close anything with my mouse

[microbillgates]

I have to use alt f4

 

[Trouble]

More information please.
What kind of mouse? Mfg. Name, Model Name, Model Number, interface (USB, usb/wireless, bluetooth, PS2, etc.,), current driver if any installed?
What kind of system? Desktop, laptop?
Have you tried other mice?
How long? Has it ever worked? Just recently? Does it work on another system? Have you tried other ports? Is it connected directly to the PC or through a Hub?
Regards
Randy