There is no latest cache settings. You have to use the link to clear the cache - meaning delete everything you see while there. Restart your browser after.
As for the XP, 7 comparison, that's irrelevant. It's like Michael Jordan saying "I'm the best at basketball, why can't I hit a 95 m.p.h. fastball?"
All it takes is one incompatible, old, notorious, or otherwise bad software or driver to ruin an otherwise perfect setup, in any OS.
If you have any antivirus other than MSE, I recommend to uninstall it in safe mode with the tool found here: