OK. Which version ? IE 9, or 10, or 11 ?
At any rates........
1. Make sure your IE is set as default browser.
click Start button > right side, click Default Programs > click Set your default programs > wait for loading > left side, under Programs, click Internet Explorer > right side, near the bottom,............
does it say "This program has all its defaults " ?
If no, click Set this program as default > click OK when done.
2. Clean your browser cache.
click Start button > in the search box, type internet options > press Enter key > at the top, click General > under Browser history > click "Delete...." button > make sure the top 4 boxes are checked. > at the bottom, click Delete > click OK when done.
Restart computer.
See if you can open links now.